xenadrine nextgen review

Xenadrine NextGen Review: Should You Buy It?

Written By : Dr Ruby Shah   ✓ Fact Checked

Xenadrine NextGen is an effective thermogenic weight loss supplement with Intelligent Delivery Nano beads that can help you lose weight. Does it really work so good as described? Read our review!

(Last Updated on November 5, 2022)

Losing weight does not come as easy as gaining it. It requires discipline, hard work, determination, and time. Even then, you might find yourself shedding off lesser pounds than you expected or non at all.

Enter weight loss supplements. There are thousands of them online and on shelves, each making all sorts of luring promises. One thing for sure: not all of them are legit.

In this Xenadrine NextGen review, we take an all-around view at the supposedly high-tech weight loss pill, including its ingredients, how it works, side effects, price, and real user reviews, among other considerations.

What Is Xenadrine NextGen?

Xenadrine NextGen is a fat burner that promises to deliver:

  • Powerful weight loss
  • Enhanced focus
  • Increased energy and sensory
  • Improved macronutrient metabolism

It is a product of Muscle Tech, a dietary supplements company marketed by Iovate Health Sciences Inc.

The Xenadrine line of supplements has many other weight loss products with an entire dedicated website 1, including Xenadrine Ultimate, Xenadrine Neuroheat, Xenadrine Pure, Xenadrine Clear, and PureXen Keto, among others

Besides weight loss supplements, MuscleTech supplies products for pre-and post-workout as well as dieting.


xenadrine nextgen label

First and foremost, we are not a fan of proprietary blends. Xenadrine ingredients come in a proprietary blend, which means we do not know the dosage.

Second thing, it’s contains quite a long list, so hold your horses.

Myristica Fragrans

This is obtained from nutmeg, a common baking spice. It is a seed that contains the active ingredient myristicin, which is believed to promote weight loss and help stop diet-induced obesity, although there is limited research to support these claims.

Euphoria Longana Extract

Euphoria Longana is the tree that produces the longan fruit, which has been a part of Traditional Chinese medicine for several millennia.

It is said that the fruit may help prevent the accumulation of fats and the rise in blood lipid levels.


Teacrine is a common ingredient in energy drinks and pre-workout formulations that is said to help maintain high dopamine levels, increased energy, better mood, and sharper mental focus.

Medium Chain Triglyceride (MCT) Oil

MCT are short-chained fatty acids that, once ingested, turn into fuel directly through the formation of ketone bodies and lipid metabolism.

This oil is trendy in keto and paleo diets and has been reported 2 to increase energy expenditure.

It is also suspected to promote satiety as well as facilitate weight loss.

Rhodiola Extract

Endemic to the Arctic and Alpine regions of Europe, America, and Asia, Rhodiola is a tonic that has been in cultures as old as Ancient Greece.

Its most popular use is helping the body deal with stress and fatigue. Still, it is also believed to increase exercise output, improve energy in the body, enhance sexual performance, and aid in weight loss.


This is a source of conjugated linoleic acid (CLA) obtained from safflower rather than meat and dairy products.

CLA’s mode of action concerning weight loss is said to come from its ability to increase specific enzymes that help with fat breakdown.

However, most of these studies 3 were not extensively done on humans, and the weight loss effects were minimal.

C. Canephora Robusta

This green coffee bean extract contains more caffeine than regular coffee, aiding in weight loss through its known thermogenic effects.

According to the official website, C. Canephora is backed by a study in which subjects who took 200mg of it were able to lose about 10.95 lbs. in 60 days, while those who took a placebo only lost 5.4 lbs.

Caffeine Anhydrous

Caffeine is a popular ingredient in most modern-day supplements to enhance focus, increase energy, and promote thermogenesis.

Xenadrine NextGen uses caffeine anhydrous in combination with C. canephora to enhance these effects.

Other Ingredients

  • Gelatin
  • Titanium dioxide
  • Silicon dioxide
  • Magnesium stearate
  • Milk and coconut ingredients
  • B-Vitamins

How Does Xenadrine NextGen Work?

Xenadrine NextGen helps with weight loss in many different ways that are critical to shedding off extra pounds.

First, it increases the rate of metabolism in the body to burn extra calories.

The supplement also aims to initiate ketosis, so the body can start burning the stored fats.

What’s more, it targets appetite suppression to minimize the number of calories taken into the body.

Then, the supplement is designed to increase energy levels, compensating for the lesser calories consumed.

It also has ingredients that may increase focus and concentration, which may help the user get through the day and work out harder.

How To Use It?

You need to take two capsules of Xenadrine NextGen twice a day, 30-60 minutes before any two of your largest meals – like breakfast and lunch.

The manufacturer advises against taking more than four capsules within a 24-hour time frame.

Also, Xenadrine NextGen produces the best outcome when used over 60 days while maintaining a low-calorie diet and regular exercise.

Are There Any Side Effects?

Here are some potential side effects of the ingredients used.

Not much is known about longana’s safety profile, but it may cause itching, hives, and swelling, although this is only based on a report by one man who was also allergic to mango and had asthma.

Based on a study of 14 healthy men, MCT oil may increase LDL cholesterol levels, posing risks to the cardiovascular system.

CLA may lead to stomach upset, headache, nausea, diarrhea, fatigue, and backache.

C. canephora robusta may cause insomnia, vomiting, restlessness, nervousness, increased heart rate, nausea, increased breathing, and upset stomach.

Caffeine anhydrous’ side effects may include headaches, nausea, lack of appetite, restlessness, insomnia, diarrhea, and anxiety.

Is Xenadrine NextGen A Scam?

Xenadrine NextGen seems like a legitimate product. Muscle Tech has a wide range of brands in various categories, which wouldn’t be the case if they didn’t know what they were doing.

The product has a solid core ingredients list, most of which have unique attributes that complement each other to support weight loss.

Moreover, Xenadrine’s pages on online retail stores and review sites are filled with positive feedback from users, indicating that the product works.

Xenadrine NextGen Reviews: What People Say About This Product?

xenadrine nextgen box

There are mixed reviews about Xenadrine NextGen online.

Of 247 customer reviews on Amazon, 54% are giving it a 5-star rating with an overall rating of 3.8 out of 5 stars.

Let’s look at some reviews.

Here are some positive ones.

James G. writes:

This is the first product I have tried in the Xenadrine line from the Hydroxycut line of products, and like all the other quality products, this did not disappoint. It provides a great energy boost as well as giving a good thermogenic feel. It did also cut food cravings some-what but not quite as much as expected. I have noticed a small weight decrease, but I mostly use these products for their mood-boosting effects. With a good eating plan, this product will produce great weight loss results.

A . Hicks left a review on Walmart. He says:

This Product is the truth!!!! I lost 30 pounds with this product in 2 1/2 months. I did this with the keto diet plus running 4 miles a day. It also gave me extra energy throughout the day. I never felt jittery. I love xenadrine and highly recommend it to someone who wants to lose weight fast.

How about the negative feedback?

Tlasy reports:

When you place your order, pay attention to the ‘color’ choice you have made. It states to buy the Nextgen at 60 capsules, it is about 30$ and states the ultimate at 120 capsules is around 15$…….in actuality, the bottle images are swapped, and you get the picture bottle, not what is labeled below it. I have ordered both bottles and have realized this trick advertising.

Xenadrine NextGen: Packages, Pricing and Where to Buy

Xenadrine NextGen comes in a pack of 60 capsules.

Each pill is a dual-release capsule with a smaller micronized powder capsule floating within the outer bio encapsulated capsule.

How much does it cost?

  • 60-count pack: under $20 + shipping and handling fee

It is available on Rite Aid, Amazon, Walmart, Muscle&Strength, and Bodybuilding.com, among other retailers.

Money-Back Guarantee and Refund Policy

According to the official website, you get a 100% money-back guarantee with some of their products – like Xenadrine-ultimate – so long as you return it to the place of purchase within 30 days and with the receipt.

However, the Xenadrine NextGen page does not give any indication of a money-back guarantee.

Pros and Cons


  • Fair price in comparison to other competitors.
  • The Xenadrine line of products dates decades, building a solid foundation for trust.
  • Patented dual-release high-potency capsule design.


  • May cause side effects such as excessive energy, irritability, and anxiety.
  • Most of the ingredients are common, and you might still be getting them from other foods.
  • Longan Extract, Theacrine, Nutmeg, and Rhodiola Rosea have been collectively assigned only 4 mg, which seems too little to have any impact.

Xenadrine NextGen Review: Should You Buy It?

Xenadrine is overall a good product in terms of the ingredients list, pricing, and design.

You can hardly get any negative reviews on the product, which means it actually gets the job done, and that’s a quality that’s becoming increasingly rare with weight loss supplements.

However, there is little evidence to support how it works and may not be an effective weight loss fat burner.

You may also need to consult your doctor before giving this product a try.

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