TruBrain review

TruBrain Review: Be Smart & Think One Step Ahead

Written By : David J. Grossklaus   ✓ Fact Checked

TruBrain is a nutraceutical combination of organic nootropics and amino acids to enhance brainpower. Find out more in this review.

(Last Updated on November 5, 2022)

We live in a world of perfection and excellence; whether it is at work, school, or home people expect the best from you.

That’s why nootropics are a good idea if you want to get ahead of the game.

They have been around in both Ayurvedic and Chinese medicine to boost cognitive performance.

Recently, the rest of the world has adopted the use of nootropics to attain peak brain performance.

One of the best nootropic supplements is TruBrain, which is designed to enhance brain performance.

It claims to be the world’s first nootropic drink-brain food in a bottle.

How effective is it?

How does it work to achieve peak performance?

Find out below.

What Is TruBrain?

TruBrain is a drink based nootropic that contains a potent blend of nutrients, cognitive enhancers, and amino acids that promise to enhance mental output.

It is designed by UCLA trained neuroscientists, Chris Thompson and Dr. Andrew Hill in 2012 and manufactured by TruBrain, a U.S. based company.

Here are the expected benefits:

  • Enhanced working memory.
  • Increased mental output.
  • Improved focus.
  • Improved energy.
  • Increased reasoning ability.
  • Reduced brain fog.
  • Improved creativity.

TruBrain Ingredients

TruBrain ingredients

TruBrain contains both synthetic and natural active ingredients that maximize brain input.

Additionally, it contains natural preservatives.

Here is an in-depth analysis of each ingredient.

Noopept (20mg)
Noopept is a synthetic nootropic that enhances cognition, improves mood, and lowers stress. It is believed to work like Piracetam, but it almost 1000 times more potent. It works by boosting the synthesis of neurotrophic factors, BDNF and NGF which increase memory. Also, it improves cognitive performance by enhancing alpha brain waves. Recent studies show that Noopept has neuroprotective properties that prevent cell death from amyloid. Thus, it helps to prevent Alzheimer’s disease. Besides, it boosts focus and prevents brain fog.
Acetyl-L-Carnitine (500mg)
Acetyl-L-Carnitine is known to offset ageing, boost mood and sharpen your mind. It boosts energy production in cells, which promotes both physical and mental function. Besides, it increases the production of acetylcholine, which improves memory and cognition. Here are some expected benefits: Supports Alzheimer’s disease treatment, Prevents depression, Reverses nerve damage, Lowers brain fatigue.
N-Acetyl Tyrosine (350mg)
N-Acetyl Tyrosine improves memory and learning and boosts attention and concentration. It is known to increase the bioavailability of Tyrosine, a dopamine precursor. Besides, it improves the production of noradrenaline from dopamine and regulates the levels of GABA and serotonin. These neurotransmitters enhance mood, boost memory, relieve anxiety and help in the treatment of ADHD.
Centrophenoxine (250mg)
Centrophenoxine is a combination of DMAE-a naturally occurring substance in the body – and auxin-a plant growth hormone. It was developed back in the 1950s to support individuals with brain ageing-related diseases like dementia and Alzheimer’s disease. It is known to speed up your recollection, improve memory, enhance mood, and boost cognition. Additionally, it reverses brain ageing by preventing free radical damage. In a snapshot: boosts acetylcholine, enhances oxygen, nutrients and blood flow in the brain, prevents oxidative stress, lowers lipofuscin.
Magnesium (200mg)
Magnesium plays a crucial role in mood and brain function. Studies show that low levels of magnesium are associated with a high risk of depression. In a 2008 1 randomized controlled trial, older individuals who were supplemented with magnesium daily reported improved mood.
L-Theanine (160mg)
L-Theanine is an amino acid mainly found in green and black tea. It is popularly used to induce relaxation. But what does science say? It has been proven to reduce anxiety and stress in individuals in stressful situations. Also, it enhances relaxation and reduces resting heart rate without drowsiness. When combined with caffeine, it boosts focus, improves alertness, and lowers fatigue. A 2016 2 study showed that L-Theanine also improves the quality of sleep.
Uridine Monophosphate (500mg)
Uridine is one of the primary building blocks of RNA. Studies show that uridine monophosphate boosts the production of acetylcholine, a neurotransmitter that improves memory and learning ability. Besides, it stimulates the growth of new neural synapses, which improve brain capacity. Uridine monophosphate stimulates the release of dopamine. Dopamine is responsible for attention span, mood, and motivation. Other benefits include: improving sleep, neuroplasticity, enhanced verbal and logical memory.
Caffeine (100mg)
Caffeine 3 is the most used psychoactive drug. It works in three primary ways. Caffeine accelerates the synthesis of neurotransmitters such as epinephrine, acetylcholine and serotonin which stimulate the brain promoting alertness, better mood and focus. It blocks adenosine-the neurotransmitter that induces sleep. Also, it enhances the density of GABA receptors and causes serotonin and dopamine receptors to be more responsive, thus improving mood. Finally, it offers neuroprotective properties by increasing BDNF (brain-derived neurotrophic factor). Thus, it protects the brain from age-related cognitive decline.
Other ingredients and flavoring
Purified water, Organic blue agave, Xylitol, Citic acid, Organic cane sugar, Natural flavor, Pink grapefruit concentrate, Monk fruit, Nisin, Polylysine.

How Does TruBrain Work?


TruBrain has four primary mechanisms of action.

TruBrain boosts blood flow to the brain, which facilitates more nutrients and oxygen to the brain.

Therefore, this enhances brain plasticity promoting better performance and cognition.

Secondly, it stimulates the release of acetylcholine, a neurotransmitter that facilitates effective communication between neurons.

This results in better memory and overall brain function.

Thirdly, it contains magnesium and tyrosine, which play a significant role in boosting mood, improving sleep and promoting neurotransmission.

Research shows that individuals who are deficient in these minerals are likely to be depressed.

Finally, TruBrain provides the brain with the necessary nutrients for brain energy and peak performance.

The manufacturer states that these mechanisms form a strong synergy to promote a healthy brain and maximize mental output.

How To Use TruBrain?

Each bottle of TruBrain contains 30ml.

The manufacturer recommends 2 drinks per day.

Here is a snapshot from the website.

You can try trubrain with or without food and at different times in the day. Most of our members like to take along with food to make sure they have some calories to take advantage of the functional benefits. Most take one right away in the morning and follow it up with one in the afternoon. Sometimes more on the big days and, of course, adding in the extra strength “boost” when they are having a case of the Mondays or for crunchtime.

You will realize results with regular and consistent use.

Consult a physician if taking medication, have a pre-existing medical condition, pregnant, or nursing.

Individuals who suffer from compromised renal function or hemophilia, and those taking MAO inhibitors should not take TruBrain.

It may increase the effects of alcohol.

Are There Any TruBrain Side Effects?

TruBrain seems pretty safe to use.

The manufacturer uses perfect dosages that are likely safe for the user.

But, keep an eye on this supplement if you are sensitive to caffeine.

Even though L-Theanine balances caffeine, it could still affect some individuals.

We also found a few reported side effects.

Here is what some users had to say:

“Unfortunately, this product left me very strung out, wound up, and irritable. It did perk me up, but no more than a cup of coffee would have.”

“Beware of side effects. This is terrible. After a while of use, I started having anxiety and panic attacks at night while sleeping. This has been a horrible situation for me. The most horrible thing is the fear that you have in the middle of the night when things are supposed to be calm. It gives you a bad crash as well. Don’t buy it!!”

TruBrain Reviews: What People Say About This Product?


TruBrain bottles

This is the first nootropic drink in the market.

Let’s see what people think about it.

Kaveri says:

“It does give you a lot of mental energy to do things. It does help you in keeping you active in whatever task you want to do for a long time. I do get light sleep on the days when I drink this. However, that does not make me feel tired the next day or anything. I stay fine and interested in carrying out things without any hesitation. I didn’t see any improvement in focus or verbal fluency. This product is a little bit expensive though for this gain.”

Ann reports:

“I fell in love with this product. Well worth the money. I started taking two A day as recommended In the box. I feel smarter because I don’t have the fogginess that clouds my days, and after long days I still feel like I’m thinking sharp, and I am making clear decisions. I’m obsessed and can’t wait to try the bars the brand supposedly sales.”

Jeremy states:

“Ok, this really works. I am seriously amazed by this product. It’s not like energy drinks, no crash later or a racing heart. I used to be an energy drink junkie, but since I found this, I don’t have to drink Red Bull or Monster anymore. Also, it doesn’t affect sleeping so that I can take it like 6 or7pm without problems. I can write a paper or read a textbook chapter faster than before. Yes, the taste is sweet but not bad at all. I love this!!”

TruBrain: Packages, Pricing and Where to Buy

TruBrain official website

TruBrain is available on the official website:

The manufacturer offers free shipping in the U.S., $10 to ship to Canada and $20 to the rest of the world.

It comes in two: drinks and bars.


  • 10 Drink trial pack: $29.00.


  • 20 Drink Pack: $49.00 per month.
  • 30 Drink Pack: $65.00 per month.
  • 60 Drink Pack: $125.00 per month.

One time purchase:

  • 20 Drink Pack: $55.00.
  • 30 Drink Pack: $75.00.
  • 60 Drink Pack: $145.00.



  • 12 bars: $49.00 per month.
  • 24 bars: $89.00 per month.

One time purchase:

  • 12 bars: $54.00.
  • 24 bars: $94.00.

The Trial Pack is only available to U.S residents.

Money-Back Guarantee and Refund Policy

Here is what the company states on their refund policy.

If you are unhappy with an order, we will do our best to make things right! Just contact us at [email protected]. Here’s what you need to know before getting in touch:

All subscriptions renew every 30 days. We are always happy to process cancellations before your subscription is renewed.

If you signed up for a trial, you will receive an email reminder two days before your trial is converted to a subscription. Please, reach out in a timely manner if you would like to cancel your subscription.

All refunds are fulfilled if you meet the following conditions.

  • Return the unopened box to the fulfillment center.
  • Packages must bear the original shrinkwrap.

You can write ‘return to sender’ or get a return label from the manufacturer for $10 – deducted from your refund.

TruBrain Pros and Cons


  • Ingredients are backed up with scientific evidence.
  • Founded by well-known scientists.
  • Transparent label.
  • Sample trial.


  • Reported side effects.
  • Issues with the billing and shipping from the official website.
  • Subscription-based model.

TruBrain Review: Should You Buy It?

TruBrain bottle on hand

TruBrain is the first world’s nootropic drink.

It is made of high-quality ingredients that are backed up by science to boost cognitive performance.

Besides, it comes with a free trial to test its effectiveness before committing to their subscription.

However, some users have reported side effects and complaints on the company’s billing and shipping services.

If you would like to purchase TruBrain, consult your physician.

Read next: Neuro Peak Review 2023: Should You Buy It?

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