Choleslo Review: Does It Really Work?

Written By : David J. Grossklaus   ✓ Fact Checked

CholesLo is the ONLY doctor formulated, “all-in-one” natural remedy to promote optimal cholesterol and lipid levels.

(Last Updated on November 20, 2023)

High cholesterol is a health issue many people may not know they have. Unless you get your cholesterol levels checked won’t know if you are affected.

It is thought that over 102 million American adults have cholesterol high cholesterol. More than 35 million of these people have levels which may put them at high risk for heart disease 1.

Your body needs cholesterol to function normally and it makes all that you need. If you have too much cholesterol it can build up in your arteries. Over time this may narrow your arteries, putting you at risk for heart disease and stroke.

Lifestyle changes may help lower cholesterol levels. These include:

  • Eating a low fat high fiber diet.
  • Maintaining a healthy weight.
  • Exercising regularly.
  • Don’t smoke, or quit if you do.

Medical intervention may be needed to treat high cholesterol. There are also cholesterol lowering supplements available that may help.

Choleslo is one such supplement, but does it work? Let’s look a bit closer at what it can do.

Read our Choleslo review.

What Is Choleslo?

Choleslo is a supplement pill from HFL Solutions. It is an online company selling health supplements. They are based in Las Vegas, Nevada.

The founder is Dr Sam Robbins. He has a PHD in Molecular and Medical Pharmacology. He is also a Registered Orthomolecular Health Practitioner (ROHP).

He tells us that:

Orthomolecular medicine describes the practice of preventing and treating disease by providing the body with optimal amounts of substances, which are natural to the body. This typically consists of food, herbs, vitamins, minerals, amino acids, etc.

Choleslo Ingredients

choleslo ingredients

Choleslo is made up of 5 blends each aimed at improving your cholesterol levels and heart health2.

Lipid Optimizing System

The first of these is a Lipid Optimizing System.

This helps to control Cholesterol, HDL/LDL & Triglycerides. It contains 746.50 Mg S of:

Red Yeast Rice

Red yeast rice contains a substance called statin. This is the main ingredient in medications used to treat high cholesterol. It can help reduce cholesterol levels and lower the risk of heart attacks. One review looked at 93 controlled trials. It found that red yeast rice can lower total cholesterol. It can also help reduce LDL or bad cholesterol. It can regulate triglycerides and increase HDL or “good” cholesterol3.

Artichoke Leaf Extract

May play a role in lowering cholesterol. It may help bile production. Bile helps your body digest fats and absorb nutrients from your food. It may also help lower blood sugar levels4.

Phytosterols Complex

These are the plant equivalent of cholesterol. They may help lower levels of bad cholesterol. It is worth noting that they may also increase the risk of cardiovascular disease and heart attack5.


This has been used in many cultures for years for its medicinal properties. One of these is the ability to lower overall and LDL (bad cholesterol) levels6.

Pantesin d-Pantethine

May help slightly lower total and LDL cholesterol levels and triglycerides. May also help increase HDL cholesterol levels.

Co-Q10 (Ubiquinone)

This is a compound that helps generate energy in your cells. It is produced naturally in your body. Its production may to decrease with age. Supplementation of CoQ10 may have many health benefits. It may help heart health and regulate blood sugar levels.


Also called Guggul Gum. This has been used for many years in Ayurvedic medicine. It may help the production of bile and removal of cholesterol7.


This ingredient is obtained from sugar cane. Studies in Cuba have shown that it may lower total and LDL cholesterol. No studies outside Cuba back this up8.

Liver Cleansing Formula

The second of the blends is a Liver Cleansing Formula.

It contains:

Milk Thistle

The active component of this ingredient is Silymarin. This is a popular health supplement for liver problems. There is little scientific evidence to show its effectiveness9.

NAC (N-Acetyl L-Cysteine)

This is an amino acid. It may help liver function and lower cholesterol10.

Insulin and Blood Sugar Regulator

The third blend is an Insulin and Blood Sugar Regulator.

It contains:

R+ Alpha Lipoic Acid (r+ ALA)

This may help control blood sugar levels11.

Inflammation Reducer

The fourth blend is an Inflammation Reducer.

It contains:


This spice is widely used in Asia. It contains curcumin. It has been shown to reduce cholesterol and inflammation12.

Mixed Tocotrienols

These may reduce cholesterol levels but the results are inconclusive.

Homocysteine Reducing Formula

The final blend is a Homocysteine Reducing Formula.

Homocysteine13 is an amino acid in your blood. High levels of it are linked to early development of heart disease. It’s associated with low levels of vitamins B6, B12, and folate, as well as renal disease. The ingredients in this blend are B vitamins and Folate.

How Does Choleslo Work?

cholesterol treatment

Choleso aims to lower cholesterol by:

  • Encourages healthy cholesterol levels.
  • Supporting liver health.
  • Improving triglyceride levels.
  • Promoting liver detoxification.
  • Balancing both LDL and HDL ratios.
  • Improving homocysteine levels.

There are indications that the individual ingredients may achieve these aims.

The company has also conducted a trial on this product. It is not published or independent.

It does show that the Choleslo works.

Choleslo Side Effects

The company states the product is safe.

They do acknowledge that some people have reported stomach upsets and aching joints.

If you are unsure about taking Choleslo, consult your physician.

Choleslo Reviews & Complaints

The company cites 617,000 satisfied customers over a 19 year period.

There are some independent Choleslo reviews for this product. They are mainly positive.

Darby writes:

I began taking CholesLo in early 2012. I had blood tests with total cholesterol of 229, LDL-103, HDL-49 and Triglycerides-387. I took CholesLo for 6 months and retested blood. Total cholesterol-163, LDL-64, HDL-63, Triglycerides-179. My doc said “I don’t know what you are doing but keep it up, your numbers haven’t been this low in 20 years.” IT WORKS PEOPLE! I had no side effects and I am going back on it now along with my husband. Totally worth the price!

Not everyone was happy with the results. Cynthia Arao in her Choleslo review mentioned that she was hoping for a better outcome.

She writes:

Overall cholesterol just dropped 10 points in a couple of months of taking Choleslo. Am very disappointed!

Choleslo Packages, Prices & Where To Buy It

  • 1 bottle$49.97 | TOTAL SAVINGS: $20.00
  • 1 bottle with “Auto-Ship” Club: $39.97 | TOTAL SAVINGS: $30.00
  • 2 bottles + 1 FREE: $99.97 | TOTAL SAVINGS: $110.00
  • 4 bottles + 3 FREE: $199.97 | TOTAL SAVINGS: $240.00

The HFL Optimized “Auto-Ship” Club is a monthly subscription plan.

As you can read at the Choleslo website this option providing couple benefits.

– Receive an ADDITIONAL 20% discount on today’s order and all future auto-ships.

– No hassle, easy and convenient shipping at a discount.

– Pay for each order only when it’s shipped.

– You have complete flexibility and may easily change the frequency or amount of each shipment (pause, add more items, ship more or less often).

– There are no commitments, contracts, obligations or fees. Cancel anytime.

What about delivery terms?

Shipping and handling charges may be applied but were not detailed. They will be added to your purchase at the checkout.

See below how the official site looks like.

Choleslo official website

Return/Refund Policy

Choleslo offers a full refund and an additional $100.00 cash back.

They also offer a 200% satisfaction guarantee. As a first time customer you have 365 days to return product that is not used.

This works in a few different ways.

  • Return all Choleslo bottles within 30 days for a full refund excluding shipping and handling. This applies to opened and unopened product.
  • Between 31-90 days you can get a full refund for unopened product. This excludes shipping and handling.
  • After 90 days you may either exchange or receive a 200% store credit. There is no expiry date on the credit. It may be used towards any product or service offered by the company.

For HFL Optimized “Auto-Ship” Club no refund will be offered once your second bottle has been shipped.

Returning product without obtaining authorization will result in a 25% restocking fee. This includes marking it return to sender. To cancel autoship your must contact the company 7 days prior to the due date for the shipment.

To qualify for the $100 cash back you must prove before and after medical tests that the product has not worked.

Full details are on the Choleslo official website under their FAQS section.

Pros & Cons


  • Clinical studies indicate that individual ingredients may work.
  • Company study has been carried out on the product.
  • Many positive customer reviews.
  • Money back guarantees.


  • Company clinical trial is not published or independent.
  • Price point may be high for some.
  • May have some side effects.

Choleslo Review: Final Verdict

choleslo bottle

If you are concerned about your cholesterol levels, lifestyle changes are a good place to start. A healthy diet and regular exercise will help.

Your physician may check your cholesterol levels. Your cholesterol or triglyceride levels may be higher than the norm. If so, you may need medication.

You may want to try a health supplement rather than medication. Follow the physicians advice.

If a supplement is suitable for you Choleslo comes from an established company.

It has many positive reviews but does not work for everyone. If you do try it and it does not work you have a money back guarantee.

We laid out the facts in this Choleslo review, will you buy it? Comment below and tell us what you think!

4 Replies to Choleslo Review: Does It Really Work?

  1. Even though it’s highly priced, and I can get statins practically free with my insurance, I’d rather try a natural supplement than a drug.
    I have my order already in transit. I hope it works .

  2. My total cholesterol was 268 in Sept.. of 2018. I have been taking CholesLo since October and after having bloodwork in April of 2019, it went down to 221. Very happy with this product.

  3. Thank you Robyn. This was a very helpful review and understandable explanation of ingredients and how it works. I bought this a few weeks ago for my husband and me and neither of us have been taking it regularly nor the correct dose. The bottle is black and the directions are written in teensy tiny font. So now I am going to write the instructions on a piece of paper and tape it to the bottle and TRY to remember to take them daily. I found your Blog and look forward to reading it.

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