Alli review

Alli Review: Is This The Best OTC Fat Burner?

Written By : Dr Ruby Shah   ✓ Fact Checked

Shred off your stubborn fat cells with the best OTC weight loss capsule. Discover more about this miraculous product in the review below.

(Last Updated on November 20, 2023)

You are devoted to an exercise routine; you’ve changed your diet and cut out fast foods. However, the number on the scale hasn’t changed.

You seem to be stuck in the never-ending cycle of dieting and training.

It’s time to try unconventional methods, including diet pills, to support your weight loss goals.

Alli is a weight loss supplement that claims to be the #1 doctor recommended OTC weight loss aid.

Do Alli pills really work? How much weight can you lose on Alli in a month?

We bring you a comprehensive Alli review: what it is, its ingredients, how it works, potential side effects if any, and whether it is a scam or not.

Let’s dive in.

What Is Alli?

alli pills

Alli is a weight loss aid that contains 60mg of orlistat, an FDA-approved weight-loss pharmaceutical drug.  Its prescription form is known as Xenical

Orlistat was FDA-approved in 1999 for long-term obesity management, in conjunction with a calorie-restricted, low-fat diet.

Alli inhibits about 25% of the fat you eat from being absorbed into your body; it mainly focuses on fat deposits in the body.

It is manufactured by GlaxoSmithKline, a company based in Philadelphia, United States.

Alli Ingredients

Alli contains one active ingredient: Orlistat.


Orlistat is an FDA approved medication for weight loss, taken alongside a low-calorie diet.

It works by blocking lipase-an enzyme that breaks down fats into free fatty acids. Without lipase, fat is not absorbed in the intestines and is excreted from the body in the form of stool.

Therefore, Alli blocks the digestion of fats in the body and prevents some fat from being absorbed. This reduces your calorie intake.

One study 1 showed that Orlistat reduced fat absorption by approximately 30 percent.

In yet another recent study 2, it was seen to have a significant reduction in weight loss, cholesterol levels, and waist circumference.

Researchers also noted that it is a well-tolerated and effective anti-obesity drug.

Besides, a study review 3 published in JAMA showed that individuals who took orlistat within 12 months lost an average of 3.4kg (7.5lbs) more significant than the placebo.

However, it was noted that weight was regained after the first year of treatment, and most individuals did not continue with this medication in the second year due to adverse gastrointestinal side effects.

How Does Alli Work?

how alli works

Alli blocks the absorption of fats in the body.

It contains orlistat-a lipase inhibitor that prevents fat breakdown and absorption in the small intestines.

Generally, dietary fat is rich in calories (9 calories per gram); thus, fewer calories are processed in the body, promoting weight loss.

But, Alli will only effectively work if you follow a low-fat, low-calorie diet.

You should expect the following Alli benefits:

  • 5 to 10% weight loss over time.
  • Blocks fat absorption by almost 25%.
  • Reduces belly fat in 12-24 weeks.
  • Reduces calories processed in the body.
  • Reduces the risk of type 2 diabetes.
  • Lowers blood pressure.
  • Reduces total and LDL cholesterol.
  • Blocks enzymes associated with weight gain.

How To Use Alli?

Alli should be used by overweight adults with a BMI of 25 and above, 18 years or older.

You should take 1 capsule with each fat-rich meal, preferably one hour before, during, or one hour after a meal.

However, you should not consume more than 3 pills daily.

The manufacturer recommends making Alli a pre-meal routine.

It should be used with a reduced-calorie, low-fat diet and exercise routine until you achieve your weight loss goals, preferably for at least 6 months.

Long-term use of Alli may reduce the absorption of fat-soluble nutrients, including A, D, E, and K. Therefore, you should add a multivitamin alongside the capsules.

Are There Any Alli Side Effects?

The manufacturer warns of some Alli side effects, including bowel changes and gastrointestinal side effects.

But, these effects seem to occur depending on how much fat you consume when taking Alli capsules and how you take these diet pills. They appear when you first start taking the capsules and subside as the body adjusts.

We did find some reported side effects such as

  • Flatulence
  • Diarrhea
  • Abdominal pain
  • Frequent bowel movements
  • Orange oily stool
  • Oil leaks
  • Shortness of breath

There were some adverse side effects reported, such as liver disease. One user reported:

I took Alli 11 years ago for less than 2 months, and I still have all the side effects. I had my gallbladder removed, diagnosed with liver disease, and so not feel like myself anymore. Do NOT take these pills.

Also, some users reported oil staining their clothes and underwear and extreme urgency to defecate. So, if you are using Alli away from home, you may need to have a pair of clothes to change.

Alli may also interfere with some medications and cause kidney toxicity.

Is Alli A Scam?

No, Alli is not a scam.

It’s no brainer that Alli works, but it comes with a lot of shortcomings.

First, Alli says that it prevents the body from absorbing fat, which means the fat you have eaten has to go somewhere-the toilet. The manufacturer clearly states that you may experience some side effects, including loose stools, gas with oily spotting, and frequent stools.

But these are not just side effects; the diet pill is designed to have these effects since fat has to be excreted from the body. Therefore, you may stain your clothes with gassy oil and frequent stools that may be difficult to control.

Again, the manufacturer says that you should follow a low-fat diet and add a multivitamin when taking Alli. This means you have an extra price to pay to cater for the fat-soluble vitamins you don’t absorb.

Alli Reviews: What People Say About This Product?

alli real users reviews

Alli has received mixed reviews online.

Of 8375 customer reviews on Amazon,65 percent are giving it 5 stars with an overall rating of  4.2 out of 5 stars.

Let’s sample some of them.

Let’s start with the positive ones.

Kiki reports:

I’ve been on this stuff for six months now and have lost 20lbs. I have not changed my eating habits, and I don’t get to exercise much, be a single mom, work full-time, and go to school full-time. So I recommend this product if you have a busy lifestyle where you can’t make those other lifestyle changes yet or a gym life and don’t mind the gradual weight loss. This will not give you instantaneous results. Like I said, 20lbs in six months. The only downfall is the oily farts, so beware and never trust a fart.

What about negative reviews?

Most users complained about side effects. Have a look.

One user writes:

I started taking Alli about 3 days ago, and I have had constant cramping and achiness in my abdomen and the side effects associated with this pill. Not only is my stool oily and runny, but I really thought maybe I had some serious intestinal problems. My stool is orangy-red, and at times I think it is bloody. I have discontinued taking Alli just to be sure this is what is causing the discoloration.

Dalms says:

I have never had kidney stones and started taking Alli 1-2 times a day a few months ago. I was just taken to the hospital for a kidney stone. I have not changed any other meds or anything else. I believe the stone is a direct result of Alli.

Alli: Packages, Pricing and Where to Buy

alli website

Alli is available on the official website:

When you click on the Buy Now option on the website, you get various online retail purchase options, including Walmart, Target, Walgreens, and CVS Pharmacy.

Besides, there is a map where you can find a local store near you.

How much does it cost you?

There are different prices since Alli is available from various retailers.


  • 60 count bottle: $39.94


  • 60 count bottle: $39.99
  • 120 count bottle: $62.99


  • 60 count bottle: $49.99
  • 120 count bottle: $71.99

CVS Pharmacy

  • 60 count bottle: $49.99
  • 120 count bottle: $69.99


  • 170 count bottle: $74.99

There are coupons available on the official website, which you can print  directly from the website and use  them instore

Money-Back Guarantee and Refund Policy

Alli does not currently offer a money-back guarantee.

Alli Pros and Cons


  • Backed by some clinical evidence.
  • FDA-approved ingredient.


  • Possible side effects.
  • Expensive.
  • Requires you to take a multivitamin.
  • No money-back guarantee.

Alli Review: Should You Buy It?

Alli is a diet pill that has shown some positive results in people. However, the adverse side effects outweigh these results.

When combined with a reduced-calorie and low-fat diet, Alli seems to support weight loss. But, it comes with baggage-side effects and nutrient deficiencies.

Many users report some gastrointestinal disturbances, which are pretty stressful and embarrassing. This has resulted in discontinuation among users. Also, Alli prevents the absorption of fat-soluble vitamins requiring you to buy an additional multivitamin.

There is no money-back guarantee, and you are required to follow a very low fat, restricted calorie diet.

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