Active Stem Review

Active Stem Review: Does It Really Work?

Written By : David J. Grossklaus   ✓ Fact Checked

Active Stem powdered supplement claims to improve cognitive function, enhance muscle strength, and improve health by boosting adult stem cells.

(Last Updated on November 20, 2023)

The name of this product may suggest some type of expensive clinical procedure.

This is not an invasive stem cell treatment which will cost millions. It is a product that apparently boosts the performance of the stem cells in your body.

The company states this product will:

  • Improve Cognitive Function
  • Enhance Joint & Muscle Strength
  • Increase Longevity

Is there any back up for these claims? Read on to see what we found out.

What Is Active Stem?

This product is a dietary supplement in powder or capsule form.

It is made by LCR Health. Their research is led by Chief Medical Officer, Dr Rand McClain.

He is a doctor of Osteopathic Medicine in California. According to his bio he his research experience is limited to 2 years as a research assistant in 2001-2003.

A search on the Better Business Bureau reveals that an alternate business name for this company is Living Cell Research. They also produce a product with same ingredients under another name.

The company claims:

That the most advanced health breakthroughs have finally reached a point where they can be made available – and affordable – to all people. Bringing high technology out of the laboratory and into the homes of the people who need them.

Lets see what is in this product.

Active Stem Ingredients

The product contains:

Vitamin D 2000 IU

It is thought that sufficient Vitamin D is obtained from diet and sun exposure. Supplementation up to 2000 IU per day is unlikely to cause harm. It may reduce the rate of fractures and falls in older adults.


Leucine belongs to a class of nutrients known as branched-chain amino acids (BCAAs) that play an important role in muscle health. It may help build and strengthen muscles. It is felt more research is needed.


Blueberry contains high levels of vitamin C. It is an antioxidants that may help fight free radical damage. It has health benefits that including improved cognitive function.

Green Tea Leaf Extract: Tea has been used for its many health benefits for many years. It contains caffeine which may make you more alert. It is also an antioxidant and may have anti inflammatory properties.


Carnosine is an amino acid that helps the muscles, heart, liver, kidneys, and brain function and grow properly. It may play a role in the aging process.

How Does Active Stem Work?

stem cell supplement

Stem cell research has been ongoing for some years.

Adult stem cells exist throughout the body after embryonic development.

  • They are found inside different types of tissue.
  • They have been found in tissues such as the brain, bone marrow, blood, blood vessels, skeletal muscles, skin, and the liver.
  • They can generate replacements for cells that are lost through normal wear and tear, injury, or disease.

The company claims that this product is a cutting edge blend of 5 powerful ingredients which, in clinical studies, have been shown to increase adult stem cell proliferation in vitro.

There is one study that has shown that nutrients can act to promote healing via an interaction with stem cells. This was however conducted in vitro i.e. in a test tube or outside a living organism.

There appear to have been no clinical tests as to whether the ingredients in this product may affect stem cells within the human body.

The clinical evidence referenced on the company website shows the benefits of some of the ingredients. There does not appear to be evidence that this supplement will provide stem cell-related benefits in humans.

Active Stem Side Effects

The company advise that this product is safe to use and produces no known side-effects.

As with any dietary supplement it is advisable to check with your doctor before taking it.

Active Stem Reviews & Complaints

There are many glowing testimonies on the company website.

T Lea writes:

I’m super happy with this product! I feel great after only 30 days of use. I no longer wake up in stiff pain from my arthritis. I am getting a better night’s sleep after suffering from severe insomnia for over a year. I have the energy to workout again. I can think more clearly, no more brain fog. I am only 43 and I was so sick with my fibromyalgia and arthritis, now I can live life again!

Active Stem: Packages, Prices & Where To Buy It

  • 1 box (1 month supply) : $69.00 (+ $3.95 Shipping and Handling)
  • 3 boxes (3 month supply) : $186.30 (FREE Shipping and Handling)
  • 6 tubes (6 month supply) : $330.15 (FREE Shipping and Handling)

Where to buy it?

We recommend to avoid places like Amazon, Walmart, GNC, or Walgreens.

Buy Active Stem at official website only, so you can be sure that you get an original product with money back guarantee.

This product is avaliable in following countries: USA, Canada, UK, Australia, New Zealand, Denmark, Germany.

See below how the official site looks like.

active stem official website

Return/Refund Policy

The products come with a 90-Day, ironclad guarantee.

That means if you aren’t completely satisfied, just call the customer service department. The customer support staff will explain how to return your product to them.

Refunds are issued on receipt of returned goods.

Active Stem Pros & Cons


  • The individual ingredients may have some health benefits.
  • There are positive customer reviews on the company website.
  • There is a 90 day money back guarantee.


  • There is no clinical study to prove that the product does what the company claims.
  • Price may be high for some.

Active Stem Review: Final Verdict

There are many stem cell supplements available on the market. Whether or not any of them work as promised appears to be the question.

There does not seem to be any clinical evidence that these supplements work.

That being said, it appears that research is still ongoing on these products. The jury may still be out as to their efficacy.

The individual ingredients in this product have been proved to give some health benefits. Customer feedback to the company is positive.

They may work for you or they may just lower your bank balance.

We laid out the facts, will you buy Active Stem? Comment below and tell us what you think!

10 Replies to Active Stem Review: Does It Really Work?

    1. Hello John. My name is Taylor with LCR Health. I am sorry to read that you would like to return your purchase. Our customer service line is 1 (800) 384-8308. We stand by our 90-day money back guarantee and I would like to get the process started for you. Please reach out to me at [email protected] so I can get started right away.

  1. Thank you for for trying to provide as much information as you can about these dubious supplements, which can sometimes do you more harm than good.

  2. This doctor performs the usual trick of spouting on his video for probably 20 minutes before getting to the point. This technique is always suspicious

  3. I am a healthy 65 year old and I take lots of supplements (which I individually try) and I live a healthy life style. I am very in tune with my body’s reactions. I tried the product for 6 months. I found that it helped my physiology and made me feel more alert, more calm and stronger.

  4. if this product is not clinically proven then why is it on the market? what is taking them this long to not have it proven. i just received this product and i am going to give it a try for mental health and physical reasons. i am 59 years old…i will get back to you in a month

    1. No vitamin on the market is FDA approved so it’s very hard to know if you are actually getting what they say in any brand of vitamins, probiotics, nutritional powders, etc on the market. There have been so many studies that have found famous brands of vitamins didn’t carry the vitamin it claimed or even remotely close to the milligrams it claims. Since this industry has taken off and multi-billion dollar industry, there seems to be more places investigating brands & their claims. With that said. I did buy this quite a few years ago. I bought the 6 pack powder form and wasn’t even close to religiously taking it but I have to admit, I did feel better when I did. I felt more energetic & alert with less brain fog without being jittery. I would have taken it more often if it wasn’t such a hassle to take. You need to mix the powder with 16 ounces of water or drink of choice. This stuff does not dissolve easily at all so I would find myself chugging it down with clumps of it and it would stick to the sides of the glass. It was better when I made smoothies in a blender but that isn’t a daily occurrence for me so if it wasn’t for the powder not dissolving I would have taken it more often. I used to be really into taking supplements & vitamins until I researched & woke up realizing I was blowing alot of money on products based on what someone was selling or what the product promised. They have since come out with a pill form in this but I have no clue if it would work the same as the powder or not but I would try that again before the powder. I’m just a customer who bought this on a whim years ago so I can only give my advice based on my personal experience. Alot of things I’ve tried didn’t do anything but I will give credit to this stuff because I did feel better when I took it. I hope this helps.

  5. I have just started this product a couple of days ago and I feel like it’s given me a little bit more energy during my day. I’m hopeful that it works 🙂

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